HitPredict

Interactor 1: PK3CD (O35904)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)
Gene: Pik3cd

Interactor 2: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27474268
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1043 Mm			1 913
+	Mm
		610624 PK3CB_MOUSE (1-1042): 0: 1137: 55.39		CBL_MOUSE (1-913): 0: 923: 100.00
+	Hs
		610280 PK3CB_HUMAN (1-1042): 0: 1110: 55.30		CBL_HUMAN (1-913): 0: 894: 91.05
+	Mm
		610557 PK3CA_MOUSE (1-1040): 0: 1052: 39.24		CBL_MOUSE (1-913): 0: 923: 100.00
+	Hs
		610279 PK3CA_HUMAN (1-1040): 0: 1048: 39.05		CBL_HUMAN (1-913): 0: 894: 91.05
+	Mm
		610648 PK3CG_MOUSE (1-1037): 0: 949: 30.30		CBL_MOUSE (1-913): 0: 923: 100.00
+	Hs
		128867 P3C2A_HUMAN (26-1039): 0: 859: 26.98		SNPC4_HUMAN (503-874): 7.25e-09: 61.9: 13.04