HitPredict

Interactor 1: TLE4 (O42478)
Transducin-like enhancer protein 4 (Enhancer of split groucho-like protein 2) (ESG2) (xESG2) (Grg-4) (XGrg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: BOWL (Q25QX6)
Protein ripply2.2 (Protein bowline)
Gene: ripply2.2

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16586348
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0017053 - transcription repressor complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 772 Xl			1 153
+	Hs
		980940 TLE4_HUMAN (1-772): 0: 564: 96.77		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		980929 TLE4_HUMAN (1-772): 0: 564: 96.77		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31
+	Hs
		980621 TLE1_HUMAN (8-772): 1.76e-179: 534: 84.85		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		883098 TLE4_HUMAN (1-772): 0: 564: 96.77		DSCR6_HUMAN (58-133): 1.26e-32: 116: 29.11
+	Hs
		980593 TLE1_HUMAN (8-772): 1.76e-179: 534: 84.85		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31
+	Hs
		883095 TLE1_HUMAN (8-772): 1.76e-179: 534: 84.85		DSCR6_HUMAN (58-133): 1.26e-32: 116: 29.11
+	Hs
		980774 TLE3_HUMAN (8-772): 1.97e-167: 503: 79.61		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		980738 TLE3_HUMAN (8-772): 1.97e-167: 503: 79.61		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31
+	Hs
		883097 TLE3_HUMAN (8-772): 1.97e-167: 503: 79.61		DSCR6_HUMAN (58-133): 1.26e-32: 116: 29.11
+	Hs
		980695 TLE2_HUMAN (8-772): 3.21e-144: 443: 64.54		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		980681 TLE2_HUMAN (8-772): 3.21e-144: 443: 64.54		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31
+	Hs
		883096 TLE2_HUMAN (8-772): 3.21e-144: 443: 64.54		DSCR6_HUMAN (58-133): 1.26e-32: 116: 29.11
+	Hs
		993463 TLE5_HUMAN (8-206): 2.58e-105: 322: 68.34		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		1132993 Q5T3G3_HUMAN (8-238): 2.99e-100: 311: 73.97		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		1127609 Q5JSZ1_HUMAN (1-211): 9.62e-99: 306: 86.67		RIPP2_HUMAN (57-143): 7.31e-46: 147: 45.65
+	Hs
		993402 TLE5_HUMAN (8-206): 2.58e-105: 322: 68.34		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31
+	Hs
		883099 TLE5_HUMAN (8-206): 2.58e-105: 322: 68.34		DSCR6_HUMAN (58-133): 1.26e-32: 116: 29.11
+	Hs
		1000245 Q5T3G3_HUMAN (8-238): 2.99e-100: 311: 73.97		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31
+	Hs
		1000243 Q5JSZ1_HUMAN (1-211): 9.62e-99: 306: 86.67		RIPP1_HUMAN (55-128): 1.32e-36: 124: 42.31