HitPredict

Interactor 1: DMC1 (O42634)
Meiotic recombination protein dmc1
Gene: DMC1

Interactor 2: RDH54 (Q09772)
Meiotic recombination protein rdh54 (EC 3.6.4.12) (ATP-dependent helicase rdh54) (Meiotically up-regulated gene 34 protein) (RAD54 protein homolog 2)
Gene: RDH54

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.605

Property	Details
Experiments	14551247, 19028606
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0007131 - reciprocal meiotic recombination GO:0016887 - ATP hydrolysis activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 332 Sp			1 811
+	Sp
		736936 RAD51_SCHPO (6-330): 1.45e-122: 358: 45.85		RDH54_SCHPO (1-811): 0: 694: 100.00
+	Hs
		988064 RAD51_HUMAN (1-330): 1.54e-126: 367: 48.34		CHD3_HUMAN (59-811): 0: 614: 18.82
+	Sc
		632564 RAD51_YEAST (2-330): 3.55e-114: 338: 45.76		RDH54_YEAST (34-768): 0: 642: 32.04
+	Sc
		632528 DMC1_YEAST (6-332): 7.92e-111: 327: 61.59		RDH54_YEAST (34-768): 0: 642: 32.04
+	Hs
		988170 RAD51_HUMAN (1-330): 1.54e-126: 367: 48.34		RA54B_HUMAN (19-770): 0: 590: 32.54
+	Ce
		107048 Q95Q25_CAEEL (3-330): 2.55e-113: 335: 46.51		G5EEN6_CAEEL (112-771): 0: 610: 30.29
+	Ce
		107037 G5EGG8_CAEEL (3-330): 4.96e-112: 331: 46.51		G5EEN6_CAEEL (112-771): 0: 610: 30.29
+	At
		96275 DMC1_ARATH (17-330): 9.47e-111: 327: 56.69		SYD_ARATH (39-771): 0: 604: 20.64
+	Hs
		1055552 DMC1_HUMAN (8-330): 1.28e-114: 337: 59.57		RA54B_HUMAN (19-770): 0: 590: 32.54
+	Mm
		936357 RAD51_MOUSE (1-330): 7.41e-127: 368: 48.04		RAD54_MOUSE (150-714): 5.62e-105: 341: 37.06
+	Sp
		736934 RAD51_SCHPO (6-330): 1.45e-122: 358: 45.85		RAD54_SCHPO (193-714): 9.33e-107: 348: 37.96
+	Hs
		988112 RAD51_HUMAN (1-330): 1.54e-126: 367: 48.34		RAD54_HUMAN (150-702): 3.38e-103: 337: 36.77
+	At
		955958 RAD51_ARATH (6-330): 3.66e-123: 358: 48.00		CHR25_ARATH (195-704): 1.89e-96: 322: 36.56
+	Sc
		632557 RAD51_YEAST (2-330): 3.55e-114: 338: 45.76		RAD54_YEAST (193-714): 3.58e-92: 311: 34.30
+	Sc
		632523 DMC1_YEAST (6-332): 7.92e-111: 327: 61.59		RAD54_YEAST (193-714): 3.58e-92: 311: 34.30
+	Ce
		108298 G5EGG8_CAEEL (3-330): 4.96e-112: 331: 46.51		Q9U2S8_CAEEL (52-715): 1.56e-81: 280: 28.95