HitPredict

Interactor 1: SMD1 (O42661)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)
Gene: SMD1

Interactor 2: PRP17 (O43071)
Pre-mRNA-processing factor 17
Gene: PRP17

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21386897
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0071013 - catalytic step 2 spliceosome GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Sp			1 558
+	Sp
		195204 SMD3_SCHPO (2-110): 3.05e-31: 108: 23.85		PRP17_SCHPO (1-558): 1.3e-139: 417: 100.00
+	Hs
		236268 LSM2_HUMAN (1-94): 7.1e-34: 114: 29.17		PRP17_HUMAN (15-558): 1.26e-118: 364: 40.07
+	Hs
		236206 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		PRP17_HUMAN (15-558): 1.26e-118: 364: 40.07
+	Hs
		236204 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		PRP17_HUMAN (15-558): 1.26e-118: 364: 40.07
+	Sc
		778619 SMD3_YEAST (2-101): 3.61e-28: 100: 25.00		PRP17_YEAST (95-558): 5.73e-92: 291: 36.25
+	Sc
		778628 SMD1_YEAST (1-114): 2.03e-25: 94.6: 39.86		PRP17_YEAST (95-558): 5.73e-92: 291: 36.25
+	Hs
		912348 SMD1_HUMAN (1-96): 9.01e-35: 117: 78.13		FBXW7_HUMAN (207-553): 1.01e-73: 250: 17.80
+	Hs
		912695 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		FBXW7_HUMAN (207-553): 1.01e-73: 250: 17.80
+	Hs
		903091 SMD1_HUMAN (1-96): 9.01e-35: 117: 78.13		WDR5_HUMAN (90-423): 1.44e-63: 213: 15.73
+	Hs
		903646 LSM4_HUMAN (1-83): 5.2e-34: 116: 27.38		WDR5_HUMAN (90-423): 1.44e-63: 213: 15.73
+	Hs
		903627 LSM2_HUMAN (1-94): 7.1e-34: 114: 29.17		WDR5_HUMAN (90-423): 1.44e-63: 213: 15.73
+	Hs
		912352 SMD1_HUMAN (1-96): 9.01e-35: 117: 78.13		SNR40_HUMAN (121-465): 2.72e-61: 207: 13.88
+	Hs
		1288409 LSM4_HUMAN (1-83): 5.2e-34: 116: 27.38		SNR40_HUMAN (121-465): 2.72e-61: 207: 13.88
+	Hs
		903093 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		WDR5_HUMAN (90-423): 1.44e-63: 213: 15.73
+	Hs
		1288404 LSM2_HUMAN (1-94): 7.1e-34: 114: 29.17		SNR40_HUMAN (121-465): 2.72e-61: 207: 13.88
+	Dm
		218374 SMD3_DROME (2-108): 1.11e-31: 110: 21.50		Q9VPL0_DROME (148-465): 2.8e-62: 210: 14.11
+	Hs
		912701 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		SNR40_HUMAN (121-465): 2.72e-61: 207: 13.88
+	Hs
		903090 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		WDR5_HUMAN (90-423): 1.44e-63: 213: 15.73
+	Hs
		912719 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		WDR83_HUMAN (300-558): 1.65e-47: 169: 22.22
+	Hs
		1103034 LSM4_HUMAN (1-83): 5.2e-34: 116: 27.38		SMU1_HUMAN (432-556): 1.6e-18: 90.6: 16.92