HitPredict

Interactor 1: SMD1 (O42661)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)
Gene: SMD1

Interactor 2: SN114 (O94316)
Pre-mRNA-splicing factor cwf10 (114 kDa U5 small nuclear ribonucleoprotein component homolog) (Complexed with cdc5 protein 10)
Gene: cwf10

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	24014766, 24442611
Identification Methods	biochemical, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	GTP_EFTU~LSM
Common GO terms	GO:0005634 - nucleus GO:0005682 - U5 snRNP GO:0005829 - cytosol GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 117 Sp			1 984
+	Hs
		912298 SMD1_HUMAN (1-96): 9.01e-35: 117: 78.13		U5S1_HUMAN (2-983): 0: 1012: 54.07
+	Hs
		1064898 LSM4_HUMAN (1-83): 5.2e-34: 116: 27.38		U5S1_HUMAN (2-983): 0: 1012: 54.07
+	Hs
		1064875 LSM2_HUMAN (1-94): 7.1e-34: 114: 29.17		U5S1_HUMAN (2-983): 0: 1012: 54.07
+	Dm
		218367 SMD3_DROME (2-108): 1.11e-31: 110: 21.50		Q9VAX8_DROME (2-983): 0: 1013: 53.20
+	Hs
		912641 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		U5S1_HUMAN (2-983): 0: 1012: 54.07
+	Hs
		911839 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		U5S1_HUMAN (2-983): 0: 1012: 54.07
+	Sp
		292972 SMD3_SCHPO (2-110): 3.05e-31: 108: 23.85		SN114_SCHPO (1-984): 0: 985: 100.00
+	Dm
		218354 SMD3_DROME (2-108): 1.11e-31: 110: 21.50		EF2_DROME (126-971): 0: 904: 35.38
+	Sc
		731734 SMD3_YEAST (2-101): 3.61e-28: 100: 25.00		SN114_YEAST (1-981): 0: 672: 33.40
+	Sc
		731722 LSM2_YEAST (1-88): 5.11e-27: 97.3: 32.22		SN114_YEAST (1-981): 0: 672: 33.40
+	Sc
		731758 SMD1_YEAST (1-114): 2.03e-25: 94.6: 39.86		SN114_YEAST (1-981): 0: 672: 33.40
+	Sc
		731729 LSM4_YEAST (1-98): 1.92e-16: 72.7: 23.85		SN114_YEAST (1-981): 0: 672: 33.40