HitPredict

Interactor 1: SMD1 (O42661)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)
Gene: SMD1

Interactor 2: PRP1 (Q12381)
Pre-mRNA-splicing factor prp1
Gene: PRP1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15755920
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 117 Sp			1 906
+	Sp
		1015547 SMD3_SCHPO (2-110): 3.05e-31: 108: 23.85		PRP1_SCHPO (1-906): 0: 554: 100.00
+	Sc
		586416 SMD3_YEAST (2-101): 3.61e-28: 100: 25.00		PRP6_YEAST (6-904): 3.92e-107: 353: 25.35
+	Sc
		586396 LSM2_YEAST (1-88): 5.11e-27: 97.3: 32.22		PRP6_YEAST (6-904): 3.92e-107: 353: 25.35
+	Sc
		586435 SMD1_YEAST (1-114): 2.03e-25: 94.6: 39.86		PRP6_YEAST (6-904): 3.92e-107: 353: 25.35
+	Sc
		586409 LSM4_YEAST (1-98): 1.92e-16: 72.7: 23.85		PRP6_YEAST (6-904): 3.92e-107: 353: 25.35
+	Hs
		300299 LSM4_HUMAN (1-83): 5.2e-34: 116: 27.38		PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15
+	Hs
		300294 LSM2_HUMAN (1-94): 7.1e-34: 114: 29.17		PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15
+	Hs
		300104 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15
+	Hs
		1318167 LSM2_HUMAN (1-94): 7.1e-34: 114: 29.17		CRNL1_HUMAN (358-893): 7.46e-37: 151: 16.32
+	Hs
		300099 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15
+	Sc
		795434 SMD3_YEAST (2-101): 3.61e-28: 100: 25.00		CLF1_YEAST (298-870): 3.23e-38: 154: 15.19
+	Sc
		746365 LSM2_YEAST (1-88): 5.11e-27: 97.3: 32.22		CLF1_YEAST (298-870): 3.23e-38: 154: 15.19
+	Sc
		970252 SMD1_YEAST (1-114): 2.03e-25: 94.6: 39.86		CLF1_YEAST (298-870): 3.23e-38: 154: 15.19
+	Hs
		911958 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		CRNL1_HUMAN (358-893): 7.46e-37: 151: 16.32
+	Hs
		912738 SMD3_HUMAN (2-107): 7.27e-32: 110: 23.59		SYF1_HUMAN (21-503): 6.01e-12: 71.9: 10.81
+	Hs
		911872 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		CTR9_HUMAN (25-518): 4.93e-14: 78.8: 11.09
+	Hs
		911970 RUXF_HUMAN (3-69): 1.72e-24: 90.4: 31.34		SYF1_HUMAN (21-503): 6.01e-12: 71.9: 10.81