Interactor 1: R113A (O15541)
E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog) (RING finger protein 113A) (Zinc finger protein 183)
Gene: RNF113A
Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.90 | 0.586 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35256949 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ubiquitin~zf-C3HC4_3 |
| Common GO terms | GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0016567 - protein ubiquitination GO:0016607 - nuclear speck GO:0061630 - ubiquitin protein ligase activity |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
