Interactor 1: KCC2 (O42844)
Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17)
Gene: cmk2

Interactor 2: HOG1 (Q09892)
Mitogen-activated protein kinase sty1 (MAP kinase sty1) (EC 2.7.11.24) (MAP kinase spc1)
Gene: sty1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 11886858, 15870269, 12589433
Identification Methods affinity chromatography technology, enzymatic study, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0010972 - negative regulation of G2/M transition of mitotic cell cycle
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 504
Sp

1 349
+ Sp
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Sc
+ Sc
+ Rn
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024