Interactor 1: SCAP (O43043)
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)
Gene: scp1

Interactor 2: SREBP (Q9UUD1)
Sterol regulatory element-binding protein 1 [Cleaved into: Processed sterol regulatory element-binding protein 1]
Gene: sre1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.692

The method score is based on:

Property Details
Experiments 25771684, 27811944, 15797383, 28202541
Identification Methods pull down, x-ray crystallography, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0008202 - steroid metabolic process
GO:0032933 - SREBP signaling pathway
GO:0032936 - SREBP-SCAP complex
GO:0098554 - cytoplasmic side of endoplasmic reticulum membrane
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1086
Sp

1 900
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024