Interactor 1: ORC5 (O43114)
Origin recognition complex subunit 5
Gene: ORC5

Interactor 2: ORC2 (Q09142)
Origin recognition complex subunit 2
Gene: ORC2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 10535928, 11717425, 11683912, 11850415, 11689699, 18723846
Identification Methods pull down, affinity chromatography technology, biochemical
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_16~ORC2, ORC2~ORC5_C
Common GO terms GO:0000785 - chromatin
GO:0003688 - DNA replication origin binding
GO:0005656 - nuclear pre-replicative complex
GO:0005664 - nuclear origin of replication recognition complex
GO:0031261 - DNA replication preinitiation complex
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 455
Sp

1 535
+ Sp
+ Sp
+ Sp
+ Hs
+ Sc
+ Dm
+ At
+ Hs
+ Sc
+ Hs
+ Dm
+ Dm
+ At
+ Sc
+ Hs
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024