HitPredict

Interactor 1: UAP2 (O43120)
Splicing factor U2AF-associated protein 2 (Cold sensitive U2 snRNA suppressor 2 homolog)
Gene: UAP2

Interactor 2: U2AF2 (P36629)
Splicing factor U2AF 59 kDa subunit (U2 auxiliary factor 59 kDa subunit) (U2AF59) (U2 snRNP auxiliary factor large subunit)
Gene: prp2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	9371883, 10923022, 11686295
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0045292 - mRNA cis splicing, via spliceosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 367 Sp			1 517
+	Hs
		641620 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		U2AF2_HUMAN (113-517): 6.48e-69: 230: 28.85
+	Hs
		641756 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		PABP4_HUMAN (55-474): 7.41e-56: 199: 10.39
+	Hs
		516364 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		PABP1_HUMAN (55-441): 2.15e-54: 195: 10.20
+	Hs
		1055876 PABP5_HUMAN (69-331): 4.31e-37: 139: 15.79		ELAV3_HUMAN (170-514): 4.07e-67: 222: 13.73
+	Hs
		641727 EWS_HUMAN (109-217): 2.03e-31: 127: 35.46		U2AF2_HUMAN (113-517): 6.48e-69: 230: 28.85
+	Hs
		967171 EWS_HUMAN (109-217): 2.03e-31: 127: 35.46		ELAV3_HUMAN (170-514): 4.07e-67: 222: 13.73
+	Hs
		1119141 PABP5_HUMAN (69-331): 4.31e-37: 139: 15.79		PAP1L_HUMAN (200-516): 8.34e-60: 209: 13.57
+	Hs
		474021 PAB4L_HUMAN (30-355): 3.21e-38: 142: 11.71		PABP4_HUMAN (55-474): 7.41e-56: 199: 10.39
+	Hs
		516635 PABP5_HUMAN (69-331): 4.31e-37: 139: 15.79		PABP1_HUMAN (55-441): 2.15e-54: 195: 10.20
+	Hs
		474019 PAB4L_HUMAN (30-355): 3.21e-38: 142: 11.71		ELAV2_HUMAN (154-393): 9.23e-39: 146: 11.46
+	Hs
		1020306 PABP5_HUMAN (69-331): 4.31e-37: 139: 15.79		ELAV2_HUMAN (154-393): 9.23e-39: 146: 11.46
+	Hs
		641773 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		RBM39_HUMAN (85-423): 6.36e-20: 94.9: 17.54
+	Dm
		1370583 Q9VM49_DROME (91-331): 1.14e-33: 133: 16.86		Q9VM49_DROME (177-512): 3.7e-28: 120: 17.85
+	Hs
		641967 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		PUF60_HUMAN (417-512): 1.59e-11: 68.7: 21.65
+	Hs
		642763 EWS_HUMAN (109-217): 2.03e-31: 127: 35.46		ELAV4_HUMAN (154-393): 1.38e-29: 121: 11.79
+	Mm
		641996 U2AF2_MOUSE (78-341): 2.06e-51: 179: 17.99		TIA1_MOUSE (426-516): 6.39e-09: 60: 14.29
+	Hs
		474034 PAB4L_HUMAN (30-355): 3.21e-38: 142: 11.71		PABP5_HUMAN (176-502): 3.66e-16: 82.2: 17.93
+	Mm
		857328 EWS_MOUSE (109-217): 5.65e-32: 128: 35.46		TIA1_MOUSE (426-516): 6.39e-09: 60: 14.29
+	Hs
		680441 EWS_HUMAN (109-217): 2.03e-31: 127: 35.46		TIA1_HUMAN (426-516): 6.74e-09: 60: 14.29