HitPredict

Interactor 1: UAP2 (O43120)
Splicing factor U2AF-associated protein 2 (Cold sensitive U2 snRNA suppressor 2 homolog)
Gene: UAP2

Interactor 2: U2AF1 (Q09176)
Splicing factor U2AF 23 kDa subunit (U2 auxiliary factor 23 kDa subunit) (U2AF23) (U2 snRNP auxiliary factor small subunit)
Gene: SPAP8A3.06

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	9371883
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-CCCH
Common GO terms	GO:0045292 - mRNA cis splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 367 Sp			1 216
+	Hs
		641723 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		U2AF1_HUMAN (1-180): 2.2e-88: 261: 59.68
+	Dm
		1098215 U2AF2_DROME (31-341): 2.44e-40: 148: 16.35		U2AF1_DROME (1-180): 2.15e-85: 255: 58.51
+	Hs
		641801 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		U2AFL_HUMAN (12-206): 2.35e-69: 221: 35.07
+	Hs
		963190 EWS_HUMAN (109-217): 2.03e-31: 127: 35.46		U2AF1_HUMAN (1-180): 2.2e-88: 261: 59.68
+	Hs
		516470 PABP1_HUMAN (101-366): 2.39e-27: 115: 10.82		U2AF1_HUMAN (1-180): 2.2e-88: 261: 59.68
+	Ce
		954186 U2AF2_CAEEL (30-341): 7.36e-35: 135: 15.41		Q9U2U0_CAEEL (2-187): 7.55e-80: 241: 52.33
+	Hs
		641773 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59
+	Hs
		641894 U2AF2_HUMAN (78-341): 1.49e-52: 182: 17.63		SPF45_HUMAN (43-145): 5.28e-25: 102: 23.81
+	Hs
		212130 EWS_HUMAN (109-217): 2.03e-31: 127: 35.46		HTSF1_HUMAN (38-205): 2.35e-34: 130: 19.05
+	Dm
		1370583 Q9VM49_DROME (91-331): 1.14e-33: 133: 16.86		Q9VM49_DROME (43-144): 4.35e-25: 103: 21.57
+	Hs
		516518 PABP1_HUMAN (101-366): 2.39e-27: 115: 10.82		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59
+	Hs
		1031328 PABP4_HUMAN (108-366): 1.6e-26: 112: 9.96		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59
+	Hs
		1020258 ELAV2_HUMAN (78-355): 2.33e-24: 104: 10.71		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59
+	Hs
		212166 RBP56_HUMAN (89-196): 8.1e-17: 83.8: 29.36		HTSF1_HUMAN (38-205): 2.35e-34: 130: 19.05
+	Hs
		726815 FUS_HUMAN (101-196): 4.3e-18: 87.6: 31.96		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59
+	Hs
		1054480 RBP56_HUMAN (89-196): 8.1e-17: 83.8: 29.36		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59
+	Hs
		726989 FUS_HUMAN (101-196): 4.3e-18: 87.6: 31.96		SPF45_HUMAN (43-145): 5.28e-25: 102: 23.81
+	Hs
		1271164 RBP56_HUMAN (89-196): 8.1e-17: 83.8: 29.36		SPF45_HUMAN (43-145): 5.28e-25: 102: 23.81
+	Dm
		1098207 CAZ_DROME (112-200): 1.47e-12: 70.3: 25.56		U2AF2_DROME (43-144): 3.46e-28: 111: 20.95
+	Hs
		1054653 PUF60_HUMAN (244-342): 1.8e-11: 67.2: 28.97		RBM39_HUMAN (39-144): 7.38e-28: 111: 23.59