HitPredict

Interactor 1: DHX15 (O43143)
ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15) (Splicing factor Prp43) (hPrp43)
Gene: DHX15

Interactor 2: AGGF1 (Q8N302)
Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (hVG5Q) (G patch domain-containing protein 7) (Vasculogenesis gene on 5q protein)
Gene: AGGF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.80	0.700

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	G-patch~HA2, G-patch~Helicase_C, G-patch~OB_NTP_bind
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 795 Hs			1 714
+	Hs
		195402 DHX15_HUMAN (1-795): 0: 856: 100.00		RBM10_HUMAN (75-684): 5.19e-74: 259: 14.61
+	Hs
		195384 DHX15_HUMAN (1-795): 0: 856: 100.00		RBM5_HUMAN (81-682): 1.52e-46: 179: 15.58
+	Hs
		958025 DHX8_HUMAN (16-783): 0: 757: 45.46		RBM10_HUMAN (75-684): 5.19e-74: 259: 14.61
+	Hs
		958093 PRP16_HUMAN (10-781): 0: 741: 39.48		RBM10_HUMAN (75-684): 5.19e-74: 259: 14.61
+	Hs
		195482 DHX15_HUMAN (1-795): 0: 856: 100.00		SUGP1_HUMAN (226-699): 2.96e-29: 125: 14.17
+	At
		97489 DEAH2_ARATH (85-793): 0: 797: 68.25		SUA_ARATH (191-610): 7.41e-44: 172: 12.53
+	Hs
		856066 DHX8_HUMAN (16-783): 0: 757: 45.46		RBM5_HUMAN (81-682): 1.52e-46: 179: 15.58
+	Hs
		195566 DHX15_HUMAN (1-795): 0: 856: 100.00		TFP11_HUMAN (538-666): 2.25e-10: 66.3: 17.86
+	Mm
		192555 DHX15_MOUSE (1-795): 0: 851: 99.62		TFP11_MOUSE (455-666): 2.44e-11: 69.3: 16.98
+	Sc
		859395 PRP43_YEAST (47-792): 0: 740: 59.89		SQS1_YEAST (367-660): 3.89e-46: 177: 19.29
+	Hs
		1055419 DHX8_HUMAN (16-783): 0: 757: 45.46		SUGP1_HUMAN (226-699): 2.96e-29: 125: 14.17
+	Sp
		194935 DHX15_SCHPO (72-793): 0: 748: 59.64		YKR3_SCHPO (527-703): 1.82e-28: 124: 21.16
+	Hs
		1055498 DHX8_HUMAN (16-783): 0: 757: 45.46		TFP11_HUMAN (538-666): 2.25e-10: 66.3: 17.86
+	Hs
		1055508 DHX8_HUMAN (16-783): 0: 757: 45.46		GPTC8_HUMAN (610-695): 3.63e-09: 62.4: 26.14
+	Hs
		224856 DHX16_HUMAN (10-789): 0: 736: 44.72		TFP11_HUMAN (538-666): 2.25e-10: 66.3: 17.86