HitPredict

Interactor 1: MCES (O43148)
mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p)
Gene: RNMT

Interactor 2: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.665

Property	Details
Experiments	32296183, 35271311, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 529
+	Hs
		134804 MCES_HUMAN (1-476): 0: 649: 100.00		IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38
+	Hs
		195612 MCES_HUMAN (1-476): 0: 649: 100.00		IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37
+	Hs
		168601 MCES_HUMAN (1-476): 0: 649: 100.00		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02
+	Hs
		195633 MCES_HUMAN (1-476): 0: 649: 100.00		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	At
		1280916 MCES1_ARATH (134-475): 1.54e-126: 374: 34.76		IMPA1_ARATH (1-529): 3.69e-156: 457: 45.00