Interactor 1: MCES (O43148)
mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p)
Gene: RNMT

Interactor 2: RAMAC (Q9BTL3)
RNA guanine-N7 methyltransferase activating subunit (Protein FAM103A1) (RNA guanine-7 methyltransferase activating subunit) (RNMT-activating mRNA cap methyltransferase subunit) (RNMT-activating mini protein) (RAM)
Gene: RAMAC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 0.90 0.881

The method score is based on:

Property Details
Experiments 28514442, 32296183, 30021884, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pox_MCEL~RAM
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0006370 - 7-methylguanosine mRNA capping
GO:0031533 - mRNA capping enzyme complex
Homologous interactions 0

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Last updated: 15 Jul 2024