HitPredict

Interactor 1: FLRT2 (O43155)
Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin-like domain-containing leucine-rich transmembrane protein 2)
Gene: FLRT2

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0043005 - neuron projection GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 660 Hs			1 192
+	Hs
		195859 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		195849 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		195866 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		195860 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		195856 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		195857 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		195848 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		195850 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		951411 FLRT3_HUMAN (9-660): 3.5e-123: 381: 44.06		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		925357 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545442 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		1150801 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		892431 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		951079 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		894129 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		900582 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436360 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		564572 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		925336 PPR29_HUMAN (47-207): 5.33e-15: 81: 21.39		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		951056 PPR29_HUMAN (47-207): 5.33e-15: 81: 21.39		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79