HitPredict

Interactor 1: TTI1 (O43156)
TELO2-interacting protein 1 homolog (Protein SMG10)
Gene: TTI1

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	28561026, 17643375, 20371770, 20801936
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0050821 - protein stabilization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 456
+	Hs
		195951 TTI1_HUMAN (1-1089): 0: 1217: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Dm
		1366581 Q9VH80_DROME (14-1046): 0: 920: 20.66		RUVB1_DROME (1-455): 0: 660: 79.56
+	Dm
		1358866 Q9VH80_DROME (14-1046): 0: 920: 20.66		RUVB2_DROME (5-455): 0: 640: 45.25
+	Sp
		293729 TTI1_SCHPO (22-1082): 0: 788: 18.28		RUVB1_SCHPO (1-456): 0: 671: 69.96
+	Sp
		293725 TTI1_SCHPO (22-1082): 0: 788: 18.28		RUVB2_SCHPO (1-455): 0: 639: 42.45
+	Sc
		732574 TTI1_YEAST (30-1043): 0: 762: 17.34		RUVB2_YEAST (5-455): 0: 627: 41.72