Interactor 1: PLXB1 (O43157)
Plexin-B1 (Semaphorin receptor SEP)
Gene: PLXNB1
Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.86 | 1.00 | 0.931 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12730235, 22807448, 25531777, 14732713, 29040270 |
Identification Methods | pull down, affinity chromatography technology, anti tag coimmunoprecipitation, affinity technology, isothermal titration calorimetry, molecular sieving, coimmunoprecipitation, two hybrid |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Plexin_cytopl~Ras, Plexin_RBD~Ras, Ras~TIG |
Common GO terms | GO:0005886 - plasma membrane GO:0007162 - negative regulation of cell adhesion GO:0016477 - cell migration |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024