Interactor 1: PLXB1 (O43157)
Plexin-B1 (Semaphorin receptor SEP)
Gene: PLXNB1

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 12730235, 22807448, 25531777, 14732713, 29040270
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, affinity technology, isothermal titration calorimetry, molecular sieving, coimmunoprecipitation, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Plexin_cytopl~Ras, Plexin_RBD~Ras, Ras~TIG
Common GO terms GO:0005886 - plasma membrane
GO:0007162 - negative regulation of cell adhesion
GO:0016477 - cell migration
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2135
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024