HitPredict

Interactor 1: SI1L1 (O43166)
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)
Gene: SIPA1L1

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1804 Hs			1 246
+	Hs
		196427 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		196429 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		196402 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		196426 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		196432 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		196406 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		910116 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683781 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927611 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		647347 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		905209 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982577 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684372 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		230231 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		230208 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		230235 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		230206 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		230229 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		230239 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		230209 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62