HitPredict

Interactor 1: ZBT24 (O43167)
Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450)
Gene: ZBTB24

Interactor 2: TZAP (P10074)
Telomere zinc finger-associated protein (TZAP) (Krueppel-related zinc finger protein 3) (hKR3) (Zinc finger and BTB domain-containing protein 48) (Zinc finger protein 855)
Gene: ZBTB48

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~BTB, zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 697 Hs			1 688
+	Hs
		563279 ZNF16_HUMAN (172-696): 0: 569: 22.65		ZNF7_HUMAN (112-602): 3e-143: 435: 24.54
+	Hs
		1343651 PRDM9_HUMAN (123-573): 1.56e-162: 492: 27.77		PRDM9_HUMAN (323-686): 5.59e-129: 404: 29.70
+	Hs
		64162 ZN430_HUMAN (234-479): 5.33e-92: 298: 33.74		ZN726_HUMAN (25-545): 7.75e-166: 491: 21.95
+	Hs
		196673 ZBT24_HUMAN (1-697): 0: 637: 100.00		ZNF71_HUMAN (290-516): 1.37e-38: 151: 37.00
+	Hs
		565101 ZNF71_HUMAN (328-631): 4.29e-112: 349: 29.81		ZNF7_HUMAN (112-602): 3e-143: 435: 24.54
+	Hs
		1239558 ZFP62_HUMAN (174-686): 9.91e-168: 505: 21.80		ZNF71_HUMAN (290-516): 1.37e-38: 151: 37.00
+	Hs
		200271 ZN264_HUMAN (134-584): 7.72e-134: 409: 27.35		ZN175_HUMAN (290-533): 5.45e-45: 173: 36.89
+	Hs
		1024287 ZBT17_HUMAN (14-635): 3.96e-159: 480: 24.10		ZBT17_HUMAN (578-687): 3.34e-15: 81.6: 19.83
+	Hs
		1343989 ZNF71_HUMAN (328-631): 4.29e-112: 349: 29.81		ZNF71_HUMAN (290-516): 1.37e-38: 151: 37.00
+	Hs
		200253 ZN264_HUMAN (134-584): 7.72e-134: 409: 27.35		ZN460_HUMAN (471-601): 3.62e-15: 80.9: 34.82
+	Hs
		1169142 ZNF71_HUMAN (328-631): 4.29e-112: 349: 29.81		ZFP2_HUMAN (405-610): 1.53e-30: 127: 34.47
+	Hs
		1055932 ZNF74_HUMAN (242-541): 1.9e-127: 393: 38.76		ZN460_HUMAN (471-601): 3.62e-15: 80.9: 34.82
+	Hs
		1305550 ZNF71_HUMAN (328-631): 4.29e-112: 349: 29.81		ZN184_HUMAN (5-175): 1.78e-23: 107: 9.78
+	Hs
		977954 ZNF92_HUMAN (236-532): 1e-109: 345: 34.65		ZN460_HUMAN (471-601): 3.62e-15: 80.9: 34.82
+	Hs
		1055984 ZN430_HUMAN (234-479): 5.33e-92: 298: 33.74		ZN460_HUMAN (471-601): 3.62e-15: 80.9: 34.82