HitPredict

Interactor 1: PRP4 (O43172)
U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
Gene: PRPF4

Interactor 2: PRP31 (Q8WWY3)
U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31)
Gene: PRPF31

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 26496610, 19615732, 16723661, 28514442, 33961781
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0015030 - Cajal body
GO:0016607 - nuclear speck
and 3 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 522
Hs

1 499
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024