HitPredict

Interactor 1: PRP4 (O43172)
U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
Gene: PRPF4

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 28514442, 35271311, 37689310, 33961781, 19615732
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006396 - RNA processing
and 3 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 522
Hs

1 357
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024