HitPredict

Interactor 1: PRP4 (O43172)
U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
Gene: PRPF4

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 29395067, 33961781, 19615732
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0017070 - U6 snRNA binding
GO:0046540 - U4/U6 x U5 tri-snRNP complex
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 522
Hs

1 95
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024