Interactor 1: SIA8C (O43173)
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8-sialyltransferase III) (Ganglioside GD3 synthase ST8SIA3) (EC 2.4.3.8) (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (Sia-a2,3-Gal-b1,4-Glc-NAc-R:a2,8-sialyltransferase) (hST8Sia III) (Sialyltransferase 8C) (SIAT8-C) (Sialyltransferase St8Sia III) (ST8SiaIII)
Gene: ST8SIA3

Interactor 2: SIA8C (O43173)
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8-sialyltransferase III) (Ganglioside GD3 synthase ST8SIA3) (EC 2.4.3.8) (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (Sia-a2,3-Gal-b1,4-Glc-NAc-R:a2,8-sialyltransferase) (hST8Sia III) (Sialyltransferase 8C) (SIAT8-C) (Sialyltransferase St8Sia III) (ST8SiaIII)
Gene: ST8SIA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 26192331
Identification Methods static light scattering, x-ray crystallography, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Glyco_transf_29~Glyco_transf_29
Common GO terms GO:0000139 - Golgi membrane
GO:0001574 - ganglioside biosynthetic process
GO:0003828 - alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0006486 - protein glycosylation
GO:0006491 - N-glycan processing
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 380
Hs

1 380
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024