HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010468 - regulation of gene expression
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 454
+	Hs
		197180 SERA_HUMAN (1-533): 0: 667: 100.00		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		346351 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346702 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348136 GRHPR_HUMAN (6-316): 6.21e-117: 350: 28.66		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00