HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007420 - brain development GO:0010468 - regulation of gene expression
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 326
+	Hs
		197380 SERA_HUMAN (1-533): 0: 667: 100.00		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		1032492 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		PCGF5_HUMAN (1-228): 9.27e-56: 183: 30.44
+	Hs
		584947 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Mm
		881368 CTBP2_MOUSE (21-383): 7.94e-122: 367: 28.57		RING2_MOUSE (7-227): 5.77e-50: 171: 16.61
+	Mm
		1265262 Q91YZ2_MOUSE (21-383): 6.14e-122: 366: 28.57		RING2_MOUSE (7-227): 5.77e-50: 171: 16.61
+	Hs
		1032573 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		987964 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		RING1_HUMAN (7-115): 2.38e-30: 120: 25.46