HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20020773
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010468 - regulation of gene expression
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 414
+	Hs
		852042 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57
+	Dm
		220634 CTBP_DROME (4-319): 1.05e-102: 318: 28.10		RB27C_DROME (99-400): 4.23e-73: 236: 28.17
+	Dm
		1369503 Q9VKI8_DROME (5-322): 2.08e-118: 353: 52.76		Q9W1I0_DROME (4-323): 2.53e-60: 200: 50.00
+	Hs
		69776 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		B1ANR0_HUMAN (98-274): 1.63e-37: 145: 19.02
+	Mm
		292162 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		TIA1_MOUSE (99-413): 1.08e-36: 139: 12.92
+	Hs
		516496 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		101719 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		F8VZ49_HUMAN (2-184): 3.76e-24: 101: 22.22
+	Hs
		881252 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		MSI2H_HUMAN (41-207): 5.16e-20: 92.2: 23.81