HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070314 - G1 to G0 transition
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 746
+	Hs
		1032431 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Sc
		755774 SER33_YEAST (7-357): 5.22e-126: 378: 30.41		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Hs
		881299 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27
+	Hs
		881258 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		1032620 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27
+	Hs
		1032558 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		57010 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		A2ABF8_HUMAN (467-732): 2.13e-68: 247: 24.21
+	Hs
		975242 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54