HitPredict

Interactor 1: ADA12 (O43184)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
Gene: ADAM12

Interactor 2: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25825872
Identification Methods	phage display, peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 909 Hs			1 526
+	Hs
		197583 ADA12_HUMAN (1-909): 0: 665: 100.00		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		197579 ADA12_HUMAN (1-909): 0: 665: 100.00		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		197580 ADA12_HUMAN (1-909): 0: 665: 100.00		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		442882 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		HCK_HUMAN (1-526): 0: 635: 100.00
+	Hs
		442890 ADA22_HUMAN (3-863): 2.63e-147: 460: 26.40		HCK_HUMAN (1-526): 0: 635: 100.00
+	Hs
		523142 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		433747 ADAM9_HUMAN (36-774): 2.04e-173: 525: 37.50		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		433995 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		442824 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		HCK_HUMAN (1-526): 0: 635: 100.00
+	Hs
		522899 ADAM8_HUMAN (29-855): 4.63e-145: 452: 33.88		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		434044 ADA22_HUMAN (3-863): 2.63e-147: 460: 26.40		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		788989 ADAM9_HUMAN (36-774): 2.04e-173: 525: 37.50		TEC_HUMAN (3-520): 3.4e-162: 476: 34.20
+	Hs
		522964 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SRC_HUMAN (1-524): 0: 582: 54.51
+	Hs
		411708 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		LCK_HUMAN (23-526): 0: 581: 64.89
+	Hs
		789007 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		TEC_HUMAN (3-520): 3.4e-162: 476: 34.20
+	Hs
		433344 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		YES_HUMAN (1-524): 0: 570: 56.77
+	Hs
		412180 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		FYN_HUMAN (22-524): 0: 564: 57.79
+	Hs
		433748 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		LYN_HUMAN (22-526): 0: 554: 70.70
+	Hs
		788983 ADAM8_HUMAN (29-855): 4.63e-145: 452: 33.88		TEC_HUMAN (3-520): 3.4e-162: 476: 34.20
+	Hs
		337463 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		ABL1_HUMAN (47-523): 1.77e-166: 502: 39.38