HitPredict

Interactor 1: ADA12 (O43184)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
Gene: ADAM12

Interactor 2: SPD2A (Q5TCZ1)
SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains)
Gene: SH3PXD2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25825872
Identification Methods	phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 909 Hs			1 1133
+	Hs
		1136544 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		SPD2A_HUMAN (1-1133): 5.76e-173: 541: 100.00
+	Hs
		1034754 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SPD2A_HUMAN (1-1133): 5.76e-173: 541: 100.00
+	Hs
		197601 ADA12_HUMAN (1-909): 0: 665: 100.00		ITSN1_HUMAN (765-1133): 1.87e-22: 106: 11.47
+	Hs
		197604 ADA12_HUMAN (1-909): 0: 665: 100.00		SH319_HUMAN (139-558): 5.95e-22: 104: 12.62
+	Hs
		197624 ADA12_HUMAN (1-909): 0: 665: 100.00		ITSN2_HUMAN (58-295): 4.7e-15: 82.9: 11.77
+	Hs
		557788 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		NCK1_HUMAN (272-569): 1.62e-23: 105: 14.64
+	Hs
		537641 ADAM9_HUMAN (36-774): 2.04e-173: 525: 37.50		NCF1_HUMAN (414-661): 2.59e-14: 78.2: 15.50
+	Hs
		537670 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		NCF1_HUMAN (414-661): 2.59e-14: 78.2: 15.50
+	Hs
		1034763 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SH3R3_HUMAN (384-1130): 4.05e-32: 137: 11.21
+	Hs
		537623 ADAM8_HUMAN (29-855): 4.63e-145: 452: 33.88		NCF1_HUMAN (414-661): 2.59e-14: 78.2: 15.50
+	Hs
		1034753 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		ITSN1_HUMAN (765-1133): 1.87e-22: 106: 11.47
+	Hs
		557680 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		NCK1_HUMAN (272-569): 1.62e-23: 105: 14.64
+	Hs
		1034759 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SH3R1_HUMAN (314-1130): 5.57e-18: 91.9: 8.98
+	Hs
		537642 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		NCF1_HUMAN (414-661): 2.59e-14: 78.2: 15.50
+	Hs
		1034750 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		ARHG7_HUMAN (744-985): 6.08e-10: 65.5: 14.62
+	Hs
		152249 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		NCK1_HUMAN (272-569): 1.62e-23: 105: 14.64
+	Hs
		152297 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		SH319_HUMAN (139-558): 5.95e-22: 104: 12.62
+	Hs
		152245 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		NCF1_HUMAN (414-661): 2.59e-14: 78.2: 15.50