Interactor 1: IRAK2 (O43187)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)
Gene: IRAK2

Interactor 2: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 21903422
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 625
Hs

1 606
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Last updated: 15 Jul 2024