HitPredict

Interactor 1: PHF1 (O43189)
PHD finger protein 1 (Protein PHF1) (hPHF1) (Polycomb-like protein 1) (hPCl1)
Gene: PHF1

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	33961781, 27705803, 29846670, 24981860, 18385154, 18285464
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 567 Hs			1 425
+	Hs
		1083275 PHF19_HUMAN (30-563): 0: 662: 39.09		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1083441 MTF2_HUMAN (27-564): 0: 643: 41.14		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		197973 PHF1_HUMAN (1-567): 0: 749: 100.00		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		997758 PHF19_HUMAN (30-563): 0: 662: 39.09		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Mm
		970679 MTF2_MOUSE (27-564): 0: 654: 41.49		RBBP4_MOUSE (1-209): 1.59e-39: 148: 12.72
+	Hs
		997966 MTF2_HUMAN (27-564): 0: 643: 41.14		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Dm
		1097854 PCL_DROME (35-550): 7.94e-124: 391: 24.51		CAF1_DROME (1-209): 8.04e-42: 154: 13.16
+	Hs
		267794 CSR2B_HUMAN (192-530): 3.91e-104: 333: 19.26		TAF5L_HUMAN (32-291): 7.24e-42: 157: 16.48
+	Hs
		1202784 ASH2L_HUMAN (162-484): 9.12e-65: 224: 15.13		WDR5B_HUMAN (1-254): 1.38e-58: 196: 14.83
+	Hs
		903524 CSR2B_HUMAN (192-530): 3.91e-104: 333: 19.26		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Dm
		1358852 Q9VJ73_DROME (175-475): 4.46e-76: 258: 18.86		WDS_DROME (212-422): 1.48e-43: 157: 19.91
+	Mm
		903674 CSR2B_MOUSE (192-513): 1.24e-98: 318: 19.35		WDR5_MOUSE (311-425): 1.28e-17: 85.2: 22.61
+	Dm
		1276839 ASH2_DROME (177-457): 1.16e-71: 241: 16.89		WDS_DROME (212-422): 1.48e-43: 157: 19.91
+	Hs
		903577 ASH2L_HUMAN (162-484): 9.12e-65: 224: 15.13		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61