HitPredict

Interactor 1: DC1L2 (O43237)
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)
Gene: DYNC1LI2

Interactor 2: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 376
+	Hs
		897156 DC1L1_HUMAN (2-492): 0: 766: 62.43		ACTZ_HUMAN (1-376): 0: 771: 100.00
+	Hs
		785582 DC1L1_HUMAN (2-492): 0: 766: 62.43		ACTY_HUMAN (1-376): 0: 728: 90.43
+	Hs
		892146 DC1L1_HUMAN (2-492): 0: 766: 62.43		ACTB_HUMAN (7-376): 0: 580: 52.41
+	Hs
		930073 DC1L1_HUMAN (2-492): 0: 766: 62.43		ACTG_HUMAN (7-376): 0: 580: 52.67