HitPredict

Interactor 1: DC1L2 (O43237)
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)
Gene: DYNC1LI2

Interactor 2: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005829 - cytosol GO:0005868 - cytoplasmic dynein complex GO:0005874 - microtubule and 2 others more... GO:0016020 - membrane GO:0030286 - dynein complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 89
+	Hs
		198288 DC1L2_HUMAN (1-492): 0: 812: 100.00		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928546 DC1L1_HUMAN (2-492): 0: 766: 62.43		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1291343 DC1L1_HUMAN (2-492): 0: 766: 62.43		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26