HitPredict

Interactor 1: PSMD3 (O43242)
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)
Gene: PSMD3

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	28190767, 33141564
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 534 Hs			1 685
+	Hs
		476573 CSN3_HUMAN (226-511): 1.4e-95: 298: 20.54		UBC_HUMAN (1-685): 0: 846: 100.00
+	Sc
		477298 RPN3_YEAST (45-531): 1.11e-166: 484: 30.87		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	At
		1092162 PSD3B_ARATH (33-533): 0: 575: 42.66		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1092148 PSD3A_ARATH (33-533): 0: 574: 43.96		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		198601 PSMD3_HUMAN (1-534): 0: 642: 100.00		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		476681 PSMD3_MOUSE (1-534): 0: 633: 96.26		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		198523 PSMD3_HUMAN (1-534): 0: 642: 100.00		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Rn
		1144180 CSN3_RAT (226-511): 1.68e-95: 298: 20.54		UBC_RAT (1-108): 1.27e-29: 127: 90.74