HitPredict

Interactor 1: PSMD3 (O43242)
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)
Gene: PSMD3

Interactor 2: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.703

The method score is based on:

Property Details
Experiments 28292943, 35271311, 37071682, 33961781
Identification Methods pull down, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
and 2 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 534
Hs

1 418
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Dm
+ Dm
+ Dm
+ Dm
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024