HitPredict

Interactor 1: PSMD3 (O43242)
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)
Gene: PSMD3

Interactor 2: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

The method score is based on:

Property	Details
Experiments	35271311, 28292943, 33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 8 others more... GO:0016020 - membrane GO:0022624 - proteasome accessory complex GO:0030234 - enzyme regulator activity GO:0034774 - secretory granule lumen GO:0042176 - regulation of protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0070062 - extracellular exosome GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	534
Hs

1	908

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024