Interactor 1: PSMD3 (O43242)
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)
Gene: PSMD3

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 28292943, 33961781, 35271311, 35235311, 37071682, 18775730, 17353931
Identification Methods pull down, affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7, PCI~Rpn3_C
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0022624 - proteasome accessory complex
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 534
Hs

1 389
+ Dm
+ Hs
+ Ce
+ Sp
+ Dm
+ Sc
+ Sc
+ Mm
+ Mm
+ At
+ Hs
+ Mm
+ Hs
+ At
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024