HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: IF4G3 (O43432)
Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)
Gene: EIF4G3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 1585
+	Hs
		203335 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		IF4G3_HUMAN (1-1585): 0: 934: 100.00
+	Mm
		665767 PABP1_MOUSE (22-296): 4e-35: 138: 15.55		PAIP1_MOUSE (677-984): 5.58e-65: 228: 21.39
+	Hs
		474036 PAB4L_HUMAN (31-303): 5.12e-41: 150: 14.59		PAIP1_HUMAN (657-984): 2.87e-21: 101: 21.31
+	Hs
		1031455 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		PAIP1_HUMAN (657-984): 2.87e-21: 101: 21.31
+	Hs
		516685 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		PAIP1_HUMAN (657-984): 2.87e-21: 101: 21.31
+	Hs
		1288625 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		PAIP1_HUMAN (657-984): 2.87e-21: 101: 21.31
+	Hs
		979889 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		IF4G1_HUMAN (214-757): 1.11e-09: 65.6: 8.64
+	Hs
		516476 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		IF4G1_HUMAN (214-757): 1.11e-09: 65.6: 8.64
+	Hs
		1119144 PAP1L_HUMAN (114-204): 9.9e-17: 83.9: 22.58		PAIP1_HUMAN (657-984): 2.87e-21: 101: 21.31
+	Hs
		979904 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		IF4G1_HUMAN (214-757): 1.11e-09: 65.6: 8.64