HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Hs			1 465
+	Hs
		227532 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		62521 RFOX3_HUMAN (46-376): 1.67e-39: 144: 53.80		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227354 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226375 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228318 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226635 TIA1_HUMAN (116-302): 3.44e-26: 110: 19.17		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227450 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227193 TIAR_HUMAN (115-302): 5.03e-25: 106: 17.53		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227642 PAP1L_HUMAN (114-204): 9.9e-17: 83.9: 22.58		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227414 CIRBP_HUMAN (122-204): 2.92e-15: 74.9: 34.12		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1031383 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		1219380 SLTM_HUMAN (79-195): 6.88e-17: 84.6: 26.05		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		312462 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312493 TIA1_HUMAN (116-302): 3.44e-26: 110: 19.17		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312605 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		475708 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475288 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		981214 CP31A_ARATH (61-202): 2e-28: 115: 20.95		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	Hs
		475757 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		186465 PABP4_ARATH (121-298): 9.35e-18: 86.9: 15.14		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17