HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 449
+	Hs
		198847 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Hs
		198862 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Hs
		474021 PAB4L_HUMAN (31-303): 5.12e-41: 150: 14.59		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		516495 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		516339 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		516689 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23
+	Hs
		516635 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		1119141 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		PAP1L_HUMAN (1-446): 4e-77: 253: 12.42
+	Mm
		665745 TIA1_MOUSE (116-302): 5.05e-26: 109: 19.17		PABP1_MOUSE (1-448): 8.44e-81: 264: 12.29
+	Hs
		855233 RFOX1_HUMAN (19-390): 3.82e-40: 148: 59.46		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Mm
		193432 TIA1_MOUSE (116-302): 5.05e-26: 109: 19.17		HNRH1_MOUSE (1-449): 5.42e-73: 238: 95.99
+	Mm
		857399 TIA1_MOUSE (116-302): 5.05e-26: 109: 19.17		HNRPF_MOUSE (1-434): 3.55e-62: 208: 71.72
+	Hs
		198986 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		ESRP2_HUMAN (109-191): 5.17e-17: 85.6: 38.55
+	Hs
		198997 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		RBM12_HUMAN (111-215): 5.28e-15: 79.4: 27.52
+	Hs
		474034 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		PAB4L_HUMAN (3-188): 1.39e-38: 145: 15.03
+	Hs
		1288653 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		RBM19_HUMAN (251-371): 8.32e-18: 88.3: 26.45
+	Dm
		1370592 Q9VM49_DROME (87-202): 3.67e-33: 132: 33.06		Q9W0D6_DROME (13-200): 9.78e-15: 78.7: 17.29
+	Hs
		516355 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16