HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11875103
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030520 - estrogen receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Hs			1 530
+	Hs
		198824 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1073538 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1049498 SAFB2_HUMAN (14-203): 1.29e-41: 158: 20.51		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269750 RFOX1_HUMAN (19-390): 3.82e-40: 148: 59.46		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1031409 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269332 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369663 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369583 SAFB2_HUMAN (14-203): 1.29e-41: 158: 20.51		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		680471 TIA1_HUMAN (116-302): 3.44e-26: 110: 19.17		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369534 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368886 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		198825 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		370176 PABP5_HUMAN (16-200): 1.51e-31: 125: 14.57		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369064 TIA1_HUMAN (116-302): 3.44e-26: 110: 19.17		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782537 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Mm
		509289 PABP1_MOUSE (22-296): 4e-35: 138: 15.55		RARA_MOUSE (52-508): 5.87e-105: 324: 23.58
+	Hs
		611434 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		516359 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		487460 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487081 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59