HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: RBPMS (Q93062)
RNA-binding protein with multiple splicing (RBP-MS) (RBPMS) (Heart and RRM expressed sequence) (Hermes)
Gene: RBPMS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.970

Property	Details
Experiments	16189514, 30217970, 26186194, 28514442, 32296183, 33961781, 34133714, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 196
+	Hs
		1274293 X5D7T5_HUMAN (4-330): 1.63e-50: 176: 62.69		RBPMS_HUMAN (1-196): 1.87e-102: 295: 100.00
+	Hs
		198916 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		RBPS2_HUMAN (20-196): 1.01e-86: 255: 72.13
+	Hs
		1274296 X5DP44_HUMAN (4-330): 8.3e-45: 160: 62.39		RBPMS_HUMAN (1-196): 1.87e-102: 295: 100.00
+	Hs
		1274258 RFOX1_HUMAN (19-390): 3.82e-40: 148: 59.46		RBPMS_HUMAN (1-196): 1.87e-102: 295: 100.00
+	Hs
		1170196 RFOX1_HUMAN (19-390): 3.82e-40: 148: 59.46		RBPS2_HUMAN (20-196): 1.01e-86: 255: 72.13
+	Hs
		963537 TIAR_HUMAN (115-302): 5.03e-25: 106: 17.53		RBPS2_HUMAN (20-196): 1.01e-86: 255: 72.13