HitPredict

Interactor 1: PAPS1 (O43252)
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)]
Gene: PAPSS1

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 624 Hs			1 465
+	Hs
		226139 PAPS2_HUMAN (9-623): 0: 919: 77.24		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	At
		188370 APS3_ARATH (188-622): 0: 615: 53.30		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1092121 APS1_ARATH (188-624): 0: 598: 54.53		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1091697 APS2_ARATH (207-624): 0: 591: 54.74		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1092266 APS4_ARATH (205-621): 0: 578: 55.43		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17