Interactor 1: SIAH2 (O43255)
E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2)
Gene: SIAH2

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 33937036, 28549433, 23518348
Identification Methods affinity chromatography technology, chromatin immunoprecipitation assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:2001237 - negative regulation of extrinsic apoptotic signaling pathway
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 324
Hs

1 920
+ Hs
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+ Hs
+ Hs
+ Mm
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+ Rn

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Last updated: 15 Jul 2024