Interactor 1: SIAH2 (O43255)
E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2)
Gene: SIAH2

Interactor 2: SIAH3 (Q8IW03)
Seven in absentia homolog 3 (Siah-3)
Gene: SIAH3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36307912
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sina~Sina
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0031624 - ubiquitin conjugating enzyme binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 324
Hs

1 269
+ Hs
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+ Mm
+ Dm
+ Hs
+ At
+ At
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024