HitPredict

Interactor 1: ZW10 (O43264)
Centromere/kinetochore protein zw10 homolog
Gene: ZW10

Interactor 2: KNTC1 (P50748)
Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)
Gene: KNTC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

The method score is based on:

Property	Details
Experiments	11146660, 20696768, 15824131, 20462495
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000070 - mitotic sister chromatid segregation GO:0000922 - spindle pole GO:0005634 - nucleus GO:0005828 - kinetochore microtubule GO:0005829 - cytosol and 6 others more... GO:0007094 - mitotic spindle assembly checkpoint signaling GO:0007096 - regulation of exit from mitosis GO:0051301 - cell division GO:0051988 - regulation of attachment of spindle microtubules to kinetochore GO:0065003 - protein-containing complex assembly GO:1990423 - RZZ complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	779
Hs

1	2209

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024