Interactor 1: SPIT1 (O43278)
Kunitz-type protease inhibitor 1 (Hepatocyte growth factor activator inhibitor type 1) (HAI-1)
Gene: SPINT1

Interactor 2: NRG1 (Q02297)
Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]
Gene: NRG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0016020 - membrane
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 529
Hs

1 640
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024