HitPredict

Interactor 1: EFS (O43281)
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Gene: EFS

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23314748
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH3_9~ubiquitin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 561 Hs			1 685
+	Hs
		302245 SC31A_HUMAN (54-480): 1.05e-39: 157: 12.93		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475664 ACK1_HUMAN (9-484): 1.17e-23: 107: 14.85		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476095 SH3R3_HUMAN (12-390): 3.66e-21: 99.8: 15.01		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475943 OTOG_HUMAN (2-468): 3.64e-14: 78.2: 9.47		UBC_HUMAN (1-685): 0: 846: 100.00
+	At
		1092229 SC24C_ARATH (70-364): 4.48e-12: 71.3: 15.51		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1092118 Q9LIE8_ARATH (124-472): 5.88e-11: 67.8: 11.02		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Mm
		222822 ACK1_MOUSE (11-484): 7.98e-29: 124: 15.31		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		397932 ACK1_HUMAN (9-484): 1.17e-23: 107: 14.85		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Rn
		1144063 SYNJ1_RAT (95-481): 1.04e-18: 92.5: 11.30		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		924095 TITIN_HUMAN (67-432): 8.56e-09: 60.8: 15.12		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00