Interactor 1: M3K13 (O43283)
Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)
Gene: MAP3K13

Interactor 2: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.644

The method score is based on:

Property Details
Experiments 12492477, 32707033
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0019901 - protein kinase binding
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 966
Hs

1 256
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024